Table 3 Peak values of plasma cytokines and estimated infection date in RDP group and SDP group.
From: Cytokine cascade and networks among MSM HIV seroconverters: implications for early immunotherapy
Function | Cytokine | RDP group | SDP group | ||
|---|---|---|---|---|---|
Days | Change Folds | Days | Change Folds | ||
Inflammatory | IL-1β | 57 | 9.64 | 82 | 5.33 |
IL-6 | 82 | 5.33 | 77 | 2.44 | |
IL-12 | 57 | 5.77 | 81 | 3.13 | |
TNF-α | 30 | 2.12 | NA | NA | |
IFN-α2 | 57 | 5.47 | 81 | 2.91 | |
Chemokines | IL-8 | 30 | 1.88 | 82 | 1.81 |
Eotaxin | NA | NA | NA | NA | |
IP-10 | 30 | 3.26 | 30 | 1.20 | |
MCP-1 | 30 | 1.83 | NA | NA | |
MIP-1α | 33 | 2.63 | 81 | 2.32 | |
MIP-1β | 57 | 2.89 | 81 | 1.93 | |
Anti-inflammatory | IL-1ra | 33 | 9.06 | 81 | 7.27 |
IL-10 | 33 | 3.02 | 81 | 2.08 | |
Growth Factor | VEGF | 93 | 14.93 | 71 | 3.73 |
FGF-2 | 62 | 9.00 | 81 | 3.70 | |
Hematopoietic | IL-7 | 57 | 2.26 | 82 | 1.90 |
G-CSF | 33 | 3.10 | 81 | 2.66 | |
GM-CSF | 61 | 8.20 | 81 | 2.55 | |
Adaptive | IFN-γ | 30 | 13.77 | 81 | 2.51 |
IL-2 | 61 | 6.28 | 81 | 3.29 | |
IL-4 | 33 | 5.09 | 54 | 5.21 | |
IL-5 | 36 | 5.99 | 77 | 6.11 | |
IL-9 | 59 | 5.09 | 81 | 4.54 | |
IL-13 | 105 | 18.38 | 33 | 9.30 | |
IL-15 | 48 | 18.75 | 82 | 7.81 | |
IL-17 | 33 | 2.71 | 81 | 2.46 | |
Average | 49.6* | 6.7# | 74.9 | 3.7 | |
