Figure 1 | Scientific Reports

Figure 1

From: Coenzyme Engineering of a Hyperthermophilic 6-Phosphogluconate Dehydrogenase from NADP+ to NAD+ with Its Application to Biobatteries

Figure 1

(a) Amino acid sequence alignment of the coenzyme-binding motif of various 6PGDH enzymes. The residues composing the loop region and responsible for coenzyme recognition are boxed. Red stars represent M. thermoacetica wide-type NADP+-preferred 6PGDH and NAD+-preferred 6PGDH mutant. Blue star indicates T. maritima 6PGDH studied in this research. (b) Subalignments of key amino acid residues playing an important role in 2′–phosphate interaction. Colors in sequence logo refer to hydrophobic (black), positive charge (blue), negative charge (red) and polar (green) residues.

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