Figure 6
New bone formation induced by bone callus in nude mice as assessed by histomorphometry.
A trabecula-like pattern of new bone formation was detected by H&E staining at 8 (a1–a4) and 12 (c1–c4) weeks post-implantation. New bone (NB) area stained green in Masson staining at 8 (b1–b4) and 12 (d1–d4) weeks after implantation; quantitative analyses of NB area (e), Tb.N (f), Tb.Th (g), and Tb.Sp (h), based on Masson staining; *P < 0.05 versus the CI group by one-way analysis of variance and Least Significance Difference (LSD) test post hoc.
