Figure 1 | Scientific Reports

Figure 1

From: ApoA-I mimetic administration, but not increased apoA-I-containing HDL, inhibits tumour growth in a mouse model of inherited breast cancer

Figure 1

Effects of hApoA-I overexpression on tumour development in PyMT mice.

(a) Tumour latency in PyMT and PyMT-hApoA-I mice. (b) Mammary gland weight at the end of the study. (c) Total tumour burden in PyMT and PyMT-hApoA-I mice. (d) Each section from right inguinal mammary gland was graded according to the maximum lesion grade and classified as follows: normal, hyperplasia, adenoma and carcinoma. The percentage of mice in each histopathologic stage is shown. In (b,c), the values shown represent the mean ± SEM for 10 individual animals per group, and *indicates p ≤ 0.05 vs. the PyMT group.

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