Table 2 Body weight, food intake and serum parameters in PyMT mice treated with the apoA-I mimetic D-4F or the vehicle.

From: ApoA-I mimetic administration, but not increased apoA-I-containing HDL, inhibits tumour growth in a mouse model of inherited breast cancer

 

Vehicle

D-4F

p

Body weight (g)

22.45 ± 0.85

19.99 ± 0.25

<0.01

Food intake (g/day)

3.90 ± 0.32

4.01 ± 0.17

0.76

Total serum cholesterol (mmol/L)

2.04 ± 0.13

1.80 ± 0.09

0.15

HDL cholesterol (mmol/L)

1.59 ± 0.12

1.14 ± 0.08

<0.01

HDL mass (g/L)

2.93 ± 0.18

2.46 ± 0.14

<0.05

mApoA-I (g/L)

0.80 ± 0.09

0.79 ± 0.13

0.52

pre-β HDL levels (% of mApoA-I)

0.51 ± 0.51

3.26 ± 0.94

<0.05

  1. Values represent the mean ± SEM for 8 mice/group. mApoA-I, mouse apoA-I. Statistical significance was considered when p ≤ 0.05 vs. the vehicle.
Back to article page