Figure 3

Total fermentation time.
The plot depictures α-La fermentations at maximized productivity with yield per substrate, substrate compositions and time on the X, Y and Z axis respectively. The simulations vary greatly in total time, from a few hours to almost two weeks. Simulations with high yield per substrate do in general take longer. The rapid decline along the 60% yield (g/g) simulations seen in Figs 2 and 3 is a result of the cell growth and recombinant protein production being unable to maintain suitable productivity for prolonged fermentations.