Table 3 Interactive effect of SUA and TBIL on CVD in type 2 diabetes.

From: Interactive effect of serum uric acid and total bilirubin for cardiovascular disease in Chinese patients with type 2 diabetes

Exposures

N (%) of CVD‡

OR (95% CI)

P value

Model 1*

 SUA < 283 umol/l and TBIL ≥ 11.5 umol/l

115 (6.83)

1

 

 SUA ≥ 283 umol/l and TBIL ≥ 11.5 umol/l

156 (5.69)

0.82 (0.64,1.05)

0.1254

 SUA < 283 umol/l and TBIL < 11.5 umol/l

116 (6.95)

1.01 (0.78,1.33)

0.8934

 SUA ≥ 283 umol/l and TBIL < 11.5 umol/l

174 (28.02)

5.30 (4.10,6.86)

<0.0001

Model 2†

 SUA < 283 umol/l and TBIL ≥ 11.5 umol/l

115 (6.83)

1

 

 SUA ≥ 283 umol/l and TBIL ≥ 11.5 umol/l

156 (5.69)

0.81 (0.63,1.04)

0.1109

 SUA < 283 umol/l and TBIL < 11.5 umol/l

116 (6.95)

0.96 (0.74,1.26)

0.8182

 SUA ≥ 283 umol/l and TBIL < 11.5 umol/l l

174 (28.02)

5.18 (4.00,6.72)

<0.0001

  1. SUA, serum uric acid; TBIL, total bilirubin; CVD, cardiovascular disease; N (%), number of cases (% of number at risk); OR, odds ratios; CI, confidence interval.
  2. *Univariable model, not adjusted for any other variables.
  3. †Multivariable model, age, duration of diabetes, gender, body mass index, systolic blood pressure, diastolic blood pressure, glycated hemoglobin, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglyceride, self-monitoring, log-transformed urinary albumin to creatinine ratio, and drug use and complications as listed in Table 1,were adjusted in multivariable analysis (Valid sample size = 6707, with 6 missing ACR).
  4. ‡N (%), number of cases (% of number at risk).
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