Table 2 DR and IAP genes mRNA expression analysis in pairs of primary cancerous and normal colorectal tissues.

From: Death receptor 5 (DR5) and a 5-gene apoptotic biomarker panel with significant differential diagnostic potential in colorectal cancer

Variable

Number of patients

p value*

DR5

Higher in cancer vs normal

81

 

Lower in cancer vs normal

18

<0.0001

Approx. equal in both tissues

1

 

DR4

Higher in cancer vs normal

59

 

Lower in cancer vs normal

35

0.5485

Approx. equal in both tissues

6

 

BIRC5 /Survivin

Higher in cancer vs normal

64

 

Lower in cancer vs normal

33

0.0002

Approx. equal in both tissues

3

 

XIAP

Higher in cancer vs normal

58

 

Lower in cancer vs normal

39

0.0300

Approx. equal in both tissues

3

 

cIAP1

Higher in cancer vs normal

25

 

Lower in cancer vs normal

69

<0.0001

Approx. equal in both tissues

6

 

cIAP2

Higher in cancer vs normal

30

 

Lower in cancer vs normal

69

<0.0001

Approx. equal in both tissues

1

 
  1. *Calculated by the non-parametric Wilcoxon Signed Ranks Test.
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