Figure 6
From: Retargeted Foamy Virus Vectors Integrate Less Frequently Near Proto-oncogenes
Retargeted FVs mediate a high level of transgene expression with no evidence of vector silencing in human cord blood CD34+ cells.
Transduction efficiency based on the percent of EGFP positive cells and MFI relative to the control in (a,b) IMR90 and (c,d) CD34+ cell populations. (e) Number of vector genome copies based on a quantitative PCR assay observed in CD34+ cells. MFI; mean fluorescence intensity.
