Figure 7 | Scientific Reports

Figure 7

From: A self-assembling nanomedicine of conjugated linoleic acid-paclitaxel conjugate (CLA-PTX) with higher drug loading and carrier-free characteristic

Figure 7

In vitro cellular uptake of the CLA-PTX@PEG NPs in MDA-MB-231 (A), B16-F10 (B) and U87-MG (C) cell lines. **p < 0.01, vs Free CLA-PTX group. Free CLA-PTX: 40 mg CLA-PTX dissolved in 5 ml of CrEL/dehydrated ethanol (50:50, v/v), and then diluted with 5% glucose injection to 300 μM of CLA-PTX. This CLA-PTX solution was continue diluted with culture medium to 10 μM of CLA-PTX. CLA-PTX@PEG NPs: CLA-PTX@PEG NPs (6 mg/ml) diluted with 5% glucose injection to 300 μM of CLA-PTX. This CLA-PTX@PEG NPs was continue diluted with culture medium to 10 μM of CLA-PTX.

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