Figure 3
From: Distinct role of IL-1β in instigating disease in Sharpincpdm mice
Histological analysis of skin sections from pre-diseased and diseased Sharpincpdm mice.
(a) Representative hematoxylin and eosin (H&E) images of control, pre-diseased (d25) and diseased (d70) Sharpincpdm mice. (b) Epidermal thickness of skin sections from control, pre-diseased (d25) and diseased (d70) Sharpincpdm mice. The epidermis of the H&E sections were measured using FIJI Image J open source software. For each section, four independent measurements were taken and averaged to get a measurement of epidermis thickening. n = 4 for control, n = 4 for pre-diseased and n = 4 for diseased Sharpincpdm groups. Statistical significance was determined by Mann-Whitney testing, and P values less than 0.05 are considered statistically significant. *P < 0.05.
