Figure 2 | Scientific Reports

Figure 2

From: Sulforaphane improves chemotherapy efficacy by targeting cancer stem cell-like properties via the miR-124/IL-6R/STAT3 axis

Figure 2

SFN repressed the CDDP-induced CSC-like properties in GC cells.

(A) MGC803 cells were treated with 0, 0.5, 1, or 2 μM of CDDP for 72 h. (BD) MGC803 cells were treated with 2 μM of CDDP, 10 μM of SFN, or their combination for 72 h. (A,B) Flow cytometry analyses of the percentage of SP (upper row) and CD44+/EpCAM+ (lower row) cells in MGC803 cell populations (mean ± SD, n = 3). (C) qRT-PCR analyses of CD44 and EpCAM (mean ± SD, n = 3). *p < 0.05, **p < 0.01, and ***p < 0.001 compared with medium control MGC803 cells. (D) Western blot analysis of CD44 and EpCAM.

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