Figure 4
From: Taurine Treatment Modulates Circadian Rhythms in Mice Fed A High Fat Diet
Effects of taurine on circadian insulin secretion in vitro.
Pancreatic islets were isolated at different times of day (6:00 h, 12:00 h, 18:00 h and 24:00 h) after 10 weeks of taurine treatment and stimulated with 2.8 mM glucose (white bars) and 16.8 mM glucose (black bars) (n = 6–7 mice per group). (A) Insulin secretion from C and C+T groups. Data are expressed as mean ± SEM. Differences between 2.8 mM glucose and 16.8 mM glucose in the C (**P < 0.01, ***P < 0.001) and C+T groups (**P < 0.01, ***P < 0.001). Differences in the time of day at 2.8 mM glucose and 16.8 mM glucose in the C and C+T groups (#P < 0.05, ##P < 0.01, and ###P < 0.001 respectively). (B) Insulin secretion from HFD and HFD+T groups (n = 6–7). Differences between 2.8 mM glucose and 16.8 mM glucose in the HFD group (*P < 0.05, ***P < 0.001) and HFD+T group (*P < 0.05). Differences in the time of day at 16.8 mM glucose in HFD group (#P < 0.05, ###P < 0.001).
