Figure 6
From: Maternal High Estradiol Exposure is Associated with Elevated Thyroxine and Pax8 in Mouse Offspring
Immunohistochemical analysis of Dnmt3a and Mbd1 in thyroids of mouse offspring.
(a) Immunohistochemical analysis of Dnmt3a in mouse offspring. The expression of Dnmt3a was significantly lower in thyroids of 3- and 8-week-old mice of Ev100 group than that of the NC group in offspring (b); An obviously lower expression of Mbd1 was also found in 3-week-old offspring of Ev100 group, whereas no difference was found in 8-week-old offspring (c). In all panels, results are expressed as means ± SE. Ev100 vs. NC, **P < 0.01, Student’s t test. 400×, Black scale bar, 50 μm.
