Figure 2
Increased surface expression and activation of adhesion receptors in a2NTD treated neutrophils.
Flow cytometric analysis of the surface expression and the activation of CD11b/CD18 integrins. Neutrophils were treated with PBS (vehicle control) or a2NTD for one hour. Neutrophils were gated as CD15+/SSChigh population, and the surface expression of (a), CD18, (b), CD11b and (c), active CD11b were assessed. Representative histograms were presented from three different experiments each was done in duplicate. (d) The expression was presented as the mean fluorescence intensity relative to control ± SEM. The statistical significance was compared with vehicle control neutrophils, ***P < 0.001.
