Figure 2 | Scientific Reports

Figure 2

From: Protein tyrosine phosphatase PTPN3 promotes drug resistance and stem cell-like characteristics in ovarian cancer

Figure 2

Silencing of PTPN3 inhibits cell cycle progression in resistant ovarian cancer cells.

(A,B) The expression of PTPN3 was significantly silenced by PTPN3 esiRNA transfection using qRT-PCR analysis in both A2780CIS (A) and A2780ADR (B) cells. *P < 0.05 (t test). (C,D) Representative cell cycle analysis by flow cytometry shows that silencing PTPN3 significantly increased the G0-G1 phase cell population and decreased the S phase cell population in both A2780CIS (C) and A2780ADR (D) cells.

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