Figure 6
Stable silencing PTPN3 inhibits resistant ovarian cancer cell tumorigenicity in vivo.
(A,B) Representative tumour images and tumour growth curved showing that the tumours formed from shPTPN3 stably transfected A2780CIS cells grew significantly more slowly than those formed from shScramble control transfected A2780CIS cells. *P < 0.05 (t test). (C,D) Representative tumour images and tumour growth curves showing that the tumours formed from shPTPN3 stable transfected A2780ADR cells grew significantly more slowly than those formed from shScramble control transfected A2780ADR cells. *P < 0.05 (t test). (E) Representative images of IHC staining of tumour tissues showing that the expression of PTPN3 was significantly decreased in shPTPN3 stably transfected tumours. Scale bar = 50 μm.
