Table 3 Multivariate analyses of associations of LINC00271 with high-risk clinicopathogical factors in the TCGA and FUSCC cohorts.

From: Long intergenic non-coding RNA 271 is predictive of a poorer prognosis of papillary thyroid cancer

Variables

TCGA

FUSCC

P valuea

OR

95.0% CI for OR

P valuea

OR

95.0% CI for OR

ETEb

 LINC00271 ≥cutoff

 

1

  

1

 

 <cutoffc

0.003

2.299

1.324–3.992

0.107

2.506

0.820–7.663

LNMd

 LINC00271 ≥cutoff

 

1

  

1

 

 <cutoffe

0.037

1.713

1.033–2.841

0.007

2.554

1.300–5.018

III/IV stagef

 LINC00271 ≥cutoff

 

1

  

1

 

 <cutoffg

0.011

2.180

1.200–3.959

0.608

1.297

0.480–3.502

  1. Notes: aItalic and bold type indicates statistical significance; badjusted by age, gender, multifocality, histological subtypes, HT, LNM and BRAFV600E mutation in multivariate analysis; cLINC00271 expression level less than the best cutoff value for prediction of ETE; dadjusted by age, gender, multifocality, histological subtypes, HT, ETE, T stage and BRAFV600E mutation in multivariate analysis; fLINC00271 expression level less than the best cutoff value for prediction of LNM; fadjusted by gender, multifocality, histological subtypes, HT, ETE, LNM, T stage and BRAFV600E mutation in multivariate analysis; gLINC00271 expression level less than the best cutoff value for prediction of III/IV stage; Abbreviations: PTC, papillary thyroid cancer; TCGA, The Cancer Genomics Atlas; FUSCC, Fudan University Shanghai Cancer Center; OR, odds ratio; CI, confidence interval; HT, Hashimoto’s thyroiditis; ETE, extrathyroidal extension; LNM, lymph node metastasis; TNM, tumor-node-metastasis.
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