Figure 2

Expression profiles of mRNAs within each group and correlated interactions formed by METH-induced ncRNAs-mRNAs.

Pearson correlation scatter plot comparing log₁₀RPKM of shared pcGenes that expressed both in saline1 and saline2 samples (A, r = 0.99, P < 0.001) and in METH1 and METH2 samples (B, r = 0.99, P < 0.001) showed nearly equivalent expression profile within the samples of each group. RPKM: The number of uniquely mapped reads per kilobase per million mappable reads. Interaction networks formed by miRNA-mRNAs and lncRNAs-mRNAs were shown by the fold change of miRNAs (C, x-axis) and lncRNAs (D, x-axis) identified in NAc of mice following METH exposure^17,18 and their potential target genes with significant changes (y-axis) in response to METH (current study).