Table 1 GO enrichment of DEGs.

From: mRNA changes in nucleus accumbens related to methamphetamine addiction in mice

GO term

EF1

P –value2

Cellular component

 GO:0015934 large ribosomal subunit

3.42

3.50E-07

 GO:0033267 axon part

3.00

1.21E-07

 GO:0005840 ribosome

2.92

2.18E-11

 GO:0005743 mitochondrial inner membrane

2.86

3.38E-07

 GO:0030425 dendrite

2.86

1.25E-07

 GO:0030427 site of polarized growth

2.84

1.22E-06

 GO:0030136 clathrin-coated vesicle

2.66

2.18E-08

 GO:0045202 synapse

2.65

2.40E-06

Molecular function

 GO:0005198 structural molecule activity

2.19

2.25E-11

 GO:0019900 kinase binding

2.00

1.30E-05

Biological process

 GO:0019058 viral infectious cycle

3.79

1.48E-16

 GO:0001505 regulation of neurotransmitter levels

3.51

4.54E-11

 GO:0048167 regulation of synaptic plasticity

3.51

1.53E-06

 GO:0022415 viral reproductive process

3.43

3.50E-16

 GO:0007268 synaptic transmission

3.04

3.33E-14

 GO:0050804 regulation of synaptic transmission

2.85

1.36E-10

 GO:0023061 signal release

2.77

9.87E-09

 GO:0003001 generation of a signal involved in cell-cell signaling

2.77

9.87E-09

 GO:0051969 regulation of transmission of nerve impulse

2.63

1.76E-10

 GO:0006887 exocytosis

2.63

1.80E-06

 GO:0031644 regulation of neurological system process

2.57

1.06E-10

 GO:0015980 energy derivation by oxidation of organic compounds

2.52

2.73E-08

 GO:0048667 cell morphogenesis involved in neuron differentiation

2.44

3.57E-06

 GO:0006091 generation of precursor metabolites and energy

2.35

9.69E-10

 GO:0055114 oxidation-reduction process

2.28

1.46E-08

 GO:0007610 behavior

2.12

3.90E-10

 GO:0006412 translation

2.06

3.67E-08

  1. 1indicated enrichment factor.
  2. 2P values were calculated via hypergeometric tests and go with a correction.