Figure 5 | Scientific Reports

Figure 5

From: Aberrant SSEA-4 upregulation mediates myofibroblast activity to promote pre-cancerous oral submucous fibrosis

Figure 5

Depletion of ST3GAL2 repressed arecoline-induced myofibroblastic differentiation activity in BMFs.

(a) The silencing effect of ST3GAL2 shRNA in arecloine-treated BMFs was validated by flow cytometry. Single cell suspension of arecoline-treated BMFs infected with ST3GAL2-specific shRNA or control sh-Luc lentivirus was analyzed for collagen gel contractility (b), migration ability (c), and wound healing ability (d). *P < 0.05 Sh-Luc.+arecoline group versus Sh-Luc. group; #P < 0.05 Sh- ST3GAL2+arecoline or Sh-2+arecoline versus Sh-Luc.+arecoline group.

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