Figure 3 | Scientific Reports

Figure 3

From: Glycinergic dysfunction in a subpopulation of dorsal horn interneurons in a rat model of neuropathic pain

Figure 3

Glycinergic paired-pulse ratio (PPR) increases in radial neurons and more stimulus is required to elicit a response after PNL.

(a) Representative traces of glycinergic eIPSCs from radial neurons of control (sham, black) and nerve-injured (PNL, red) animals with amplitudes normalized to the first pulse. Scatter dot plot showing data for PPR from control (n = 6) and nerve-injured (n = 8) groups (*p < 0.05, unpaired t test). (b) Input-output curve showing reduced glycinergic transmission in radial cells from nerve-injured spinal cord at all voltages (*p < 0.05, unpaired t test at each voltage value).

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