Figure 5
Frequency of mIPSCs in radial neurons are reduced after PNL.
(a) Representative traces of glycinergic mIPSCs from radial neurons of control (black) and nerve-injured (red) animals over a 10 second period. (b) Cumulative probability distribution of glycinergic mIPSC amplitudes of all recordings (n = 10 for each group), with scatter dot plot showing average mIPSC amplitude from each recording (inset). (c) Histogram showing distribution of mIPSC amplitude over a 5 minute period for control and nerve injured groups (n = 10 per group). (d) Cumulative probability distribution of glycinergic mIPSC inter-event intervals of all recordings (n = 10 for each group), with scatter dot plot showing average mISPC frequency of each recording (inset). (e) Representative traces of single mIPSC events from control and nerve-injured animals with fitted exponential shown in grey and a scatter dot plot of decay time constants for both treatment groups (n = 10 per group). **p < 0.01; ***p < 0.001 (unpaired t tests).
