Figure 8 | Scientific Reports

Figure 8

From: Glycinergic dysfunction in a subpopulation of dorsal horn interneurons in a rat model of neuropathic pain

Figure 8

Schematic showing recording configurations used in this study and main findings.

Inhibitory neurons in lamina III were stimulated and synaptic currents in lamina II interneurons were recorded. Results show a decrease in the probability of glycine release from glycinergic neurons that synapse with radial neurons, as well as a switch to GlyRα2 subunits in radial neurons.

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