Figure 1

The phenotypic characterisation of Ank-1(MRI61689/+) mice.
The morphology of Ank-1(MRI61689/+) and Ank-1(MRI61689/MRI61689) erythrocytes under light microscopy with Giemsa stain (a) and scanning electron microscopy (b). The osmotic fragility curve of wild-type and Ank-1(MRI61689/+) erythrocytes when subjected to osmotic stress (c) (n = 5–7 per group). The in-vitro spleen retention rate of wild-type and Ank-1(MRI61689/+) erythrocytes when passing through filter beds (d) (n = 3 per group). **Indicates P < 0.01, ***indicates P < 0.001, and all error bars are standard error of mean (SEM).