Figure 3 | Scientific Reports

Figure 3

From: A novel ENU-induced ankyrin-1 mutation impairs parasite invasion and increases erythrocyte clearance during malaria infection in mice

Figure 3

The effect of Ank-1(MRI61689)mutation on the Ank-1 expression.

Quantitative PCR showing the ankyrin-1 mRNA levels in both Ank-1(MRI61689/+) and Ank-1(MRI61689/MRI61689)embryonic liver (a). The protein levels of various cytoskeletal proteins examined with Coomassie (b). Representative Western blot images for ankyrin-1 (ANK1), Band 3, alpha-spectrin (SPTA), beta-spectrin (SPTB), protein 4.2 (P 4.2) and Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) housekeeping gene in RBC membrane (c). The quantitative analysis of ankyrin-1 (d) (n = 3 per group). Error bars indicate SEM.

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