Figure 2 | Scientific Reports

Figure 2

From: Foetal programming by methyl donor deficiency produces steato-hepatitis in rats exposed to high fat diet

Figure 2

Biochemical parameters of D50 and D 185 rats.

D50 rats were born from dams fed a methyl donor deficient diet (iMDD) during pregnancy and lactation and subsequently subjected to high fat (HF) diet between D50 and D185. (A) Plasma concentrations of methylmalonic acid (MMA), homocysteine, triglycerides and cholesterol of iMDD rats were similar to those of control animals. (B) ASAT/ALAT ratio of iMDD D50 and iMDD/HF D185 rats were increased, compared to the respective control animals. (C) Free fatty acids concentration among groups was similar at D50. At D185 the free fatty acid concentration was higher in iMDD and iMDD/HF groups, compared to their respective control groups. Data are reported as means ± SD (n = 8 in each group), *p < 0.05, **p < 0.01, ***p < 0.001.

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