Scientific Reports

Table 3 Summary of recent publications on lactic acid production from agro-biomass.

From: Comparison of high-titer lactic acid fermentation from NaOH- and NH₃-H₂O₂-pretreated corncob by Bacillus coagulans using simultaneous saccharification and fermentation

Strain	Substrate	Pretreatment	Detoxification	Fermentation mode	Lactic acid			Optical purity	Ref.
Strain	Substrate	Pretreatment	Detoxification	Fermentation mode	titer (g/L)	yield (g/g)	productivity (g/L/h)	Optical purity	Ref.
B. coagulans strain IPE22	wheat straw (water insoluble solid after pretreatment)	sulfuric acid	—	SSF	38.73	0.46^a	0.43	N.D.	23
B. coagulans MXL-9	corn fiber hydrolysate	sulfuric acid	—	SHF	39	0.39^a	0.54	99% L-LA	16
B. coagulans DSM 2314	wheat straw	lime	—	fed-batch SSF	40.7	0.43^a/0.81^c	0.68	97.2% L-LA	21
B. coagulans LA204	corn stover	NaOH	water washing	fed-batch SSF	97.59	0.68^a	1.63	97.9% L-LA	12
B. coagulans JI12	hydrolysate of oil palm empty fruit bunch	sulfuric acid and phosphoric acid	—	fed-batch SHF	137.5	0.98^b	4.4	99.5% L-LA	22
Bacillus sp. strain NL01	corn stover hydrolysate	Steam explosion followed by enzyme saccharification	water washing	fed-batch SHF	75	0.75^b	1.04	N.D.	32
Lb. rhamnosus and Lb. brevis	corn stover	NaOH	water washing	fed-batch SSF	60.3	0.7^a	0.58	N.D.	33
Lb. plantarum NCIMB 8826	corn stover	NaOH	—	fed-batch SSF	61.4	0.77^d	0.32	99% D-LA	34
Lb. pentosus FL0421	corn stover	NaOH	water washing	fed-batch SSF	92.3	0.66^a	1.92	98.1% L-LA	35
P. acidilactici DQ2	corn stover	dilute sulphuric acid	bio-detoxification	SSF	101.9	0.77^e	1.06	63.4% L-LA	25
P. acidilactici TY112	corn stover	dilute sulphuric acid	bio-detoxification	SSF	104.4/77.76	0.72^e/0.65^e	1.06	99.89% L-LA	24,36
P. acidilactici ZP26	corn stover	dilute sulphuric acid	bio-detoxification	SSF	76.76	0.58^e	1.02	99.32% D-LA	36
R. oryzae HZS6	corncob hydrolysate	sulfuric acid	—	SHF	77.2	0.80^b	0.99	100% L-LA	37
B. coagulans LA204	corncob	NaOH/NH₃-H₂O₂	water washing	fed-batch SSF	120.99/118.60	0.77^a/0.74^a	1.37/1.32	98% L-LA	This study
B. coagulans LA204	corncob	NH₃-H₂O₂	—	fed-batch SSF	79.47	0.43^a	1.10	98% L-LA	This study

^ag/g total stover.
^bg/g total sugar in the hydrolysate.
^cg/g released total sugar.
^dg/g used stover.
^eg/g glucose from total cellulose. N.D.: not determined.

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