Figure 1 | Scientific Reports

Figure 1

From: Continuous exposure to non-lethal doses of sodium iodate induces retinal pigment epithelial cell dysfunction

Figure 1

Acute and prolonged effects of sodium iodate exposure on RPE cell survival.

Cell viability was assessed by MTT assay. (A) ARPE-19 cells were treated with 0–100 mM sodium iodate for 24 hours. Treatment of 20, 50 and 100 mM sodium iodate reduced ARPE-19 cell viability by 25.64%, 83.43% and 87.67%, respectively. Sodium iodate with concentration of 10 mM or below did not significantly cause reduction in RPE cell viability after 24-hour treatment. ‘**’p < 0.01; ‘***’p < 0.001. (B) ARPE-19 cells were treated continuously with 2–10 mM sodium iodate for 5 days. ARPE-19 cell viability was enhanced in 2 and 5 mM treatment groups but reduced in 10 and 20 mM groups compared to the control group (0 mM). ‘***’p < 0.001.

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