Table 3 Baseline characteristics of patients with T2DM with various KCNQ1 rs2237892 (C/T) genotypes before the administration of repaglinide (n = 305).

From: A variation in KCNQ1 gene is associated with repaglinide efficacy on insulin resistance in Chinese Type 2 Diabetes Mellitus Patients

Parameter

CC (n = 148)

CT/TT (n = 157)

P value

Sex

 Male

90

95

 

 Female

58

62

0.957b

Age (years)

49.10 ± 10.68

48.78 ± 12.93

0.812

BMI (kg/m2)

25.71 ± 3.22

26.47 ± 3.79

0.109c

WHR

0.91 ± 0.07

0.91 ± 0.06

0.901c

FPG (mM)

9.95 ± 2.62

9.88 ± 2.78

0.614c

PPG (mM)

16.52 ± 4.47

16.20 ± 4.81

0.162c

FINS (mU/l)

9.99 ± 6.90

13.93 ± 13.82

0.014*

PINS (mU/l)

37.81 ± 46.19

57.37 ± 66.45

0.002**c

HOMA-IR

4.24 ± 2.71

5.67 ± 4.92

0.046*c

HbA1c (%)

9.42 ± 1.85

9.16 ± 2.28

0.02*c

TG (mM)

2.49 ± 3.19

2.64 ± 2.66

0.182c

TC (mmol/l)

5.25 ± 1.33

5.29 ± 1.27

0.629c

HDL-c (mM)

1.43 ± 0.52

1.36 ± 0.45

0.128c

LDL-c (mM)

3.19 ± 1.12

3.21 ± 1.04

0.971c

  1. Data are given as the mean ± SD.
  2. bP values were determined using Pearson’s χ2 test.
  3. cP values were determined using the Mann-Whitney test; all other P values were assessed using independent-samples t-tests. *P < 0.05,**P < 0.01.
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