Table 1 Kinetic data for the interaction of the lectin domain of L. plantarum CMPG5300 with HIV-1 gp120 and gp41.

From: High mannose-specific lectin Msl mediates key interactions of the vaginal Lactobacillus plantarum isolate CMPG5300

 

HIV-1 gp120

HIV-1 gp41

ka (1/Ms)

kd (1/s)

KD (M)

ka (1/Ms)

kd (1/s)

KD (M)

HHA

1.66E + 06

2.19E − 03

1.32E − 09

2.75E + 06

2.29E − 03

8.36E − 10

Lectin domain of Msa

2.62E + 03

1.64E − 02

6.26E − 06

7.15E + 03

2.36E − 02

3.30E − 06

Lectin domain of Msl

3.05E + 04

5.64E − 02

1.85E − 06

2.29E + 04

2.88E − 02

1.62E − 06

  1. ka: association rate constant, kd: dissociation rate constant and KD: the binding affinity values.
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