Figure 1 | Scientific Reports

Figure 1

From: SUMO-specific protease 3 is a key regulator for hepatic lipid metabolism in non-alcoholic fatty liver disease

Figure 1

Intrahepatic SENP3 production was determined in NAFLD and controls.

Histopathology of the liver tissues from healthy liver donors (n = 3) (A) and NAFLD (n = 8) (B) were H&E stained. Intrahepatic SENP3 production from healthy liver donors (C) and NAFLD (D) were labelled immunohistochemically, with the black arrows indicated the positive labelling. Quantification of immune-staining was presented (E, p < 0.001). The corresponding H&E of the liver from ND- (n = 5) (F) and HFD-fed (n = 5) (G) rats and immunohistochemistry of SENP3 in the liver from ND- (H) and HFD-fed (I) rats and their corresponding quantification were also presented (J, p < 0.001). The hepatic protein production of SENP3 from HFD-fed and ND-fed rats was confirmed by Western blotting (K) and the quantification was presented (L, p < 0.01).

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