Figure 2 | Scientific Reports

Figure 2

From: SUMO-specific protease 3 is a key regulator for hepatic lipid metabolism in non-alcoholic fatty liver disease

Figure 2

SENP3 regulated lipid accumulation in hepatocytes.

Intrahepatic lipid was labelled with Oil red o in hepatocytes treated without FFA (A) and with FAA (B). Compared with NS-siRNA (C), FFA induced lipid accumulation was attenuated in hepatocyte transfected with SENP3-siRNA (D). Compared with PCDNA3.1 (E), FFA induced lipid content was further enhanced with GFP-SENP3 (F). Intrahepatic TG was quantified from different treatments (G). Intrahepatic SENP3 mRNA from the different treatments was quantified, using qRT-PCR (H,I).

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