Figure 4 | Scientific Reports

Figure 4

From: SUMO-specific protease 3 is a key regulator for hepatic lipid metabolism in non-alcoholic fatty liver disease

Figure 4

Top three SENP3 related genes (apoe, a2m, and tnfrsf11b) were quantified in vitro using qRT-PCR. mRNA of apoe (A), a2m (B), and tnfrsf11b (C) in the hepatocytes was silenced with SENP3-siRNA transfection, but increased with GFP-SENP3 transfection. To determine the effects of SENP3 in lipid regulation, apoe (D), a2m (E) and tnfrsf11b (F) mRNA levels were further quantified in control, SENP3-siRNA transfected and GFP-SENP3 transfected hepatocytes with/without FFA stimulation.

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