Table 1 The gene expression and potential clinical application of 11 selected secreted genes.
Gene Symbol | OE_Gfold | OE_Log2fdc | OE_group1 | KD_Gfold | KD_Log2fdc | KD_group2 | Location | biomarker | Type |
|---|---|---|---|---|---|---|---|---|---|
A2M | 1.52154 | 1.64718 | (12.9488)/(4.10322) | −4.26924 | −4.79629 | (0.151817)/(4.10322) | extracellular space |  | transporter |
TNFRSF11B | 1.54377 | 1.80015 | (6.52981)/(1.85577) | −1.39613 | −1.86165 | (0.533395)/(1.85577) | plasma membrane | diagnosis | transmembrane receptor |
APOE | 1.14086 | 1.55592 | (4.24542)/(1.42182) | −0.92172 | −1.61638 | (0.478918)/(1.42182) | extracellular space | diagnosis, progression | transporter |
SEPP1 | 0.528556 | 0.768941 | (4.82016)/(2.80529) | −1.7658 | −2.19251 | (0.641311)/(2.80529) | extracellular space |  | other |
CASP9 | 0.452835 | 0.545562 | (27.7131)/(18.8567) | −1.6161 | −1.76155 | (5.86863)/(18.8567) | cytoplasm | diagnosis | peptidase |
FABP3 | 0.305249 | 0.37913 | (88.3177)/(67.4482) | −1.61108 | −1.72339 | (21.5628)/(67.4482) | cytoplasm | diagnosis | transporter |
F3 | 0.06848 | 0.142588 | (36.7201)/(33.0407) | 1.56437 | 1.62653 | (107.78)/(33.0407) | plasma membrane | Â | transmembrane receptor |
SERPINE1 | −0.21564 | −0.3676 | (5.48462)/(7.03013) | 1.38929 | 1.50678 | (21.1157)/(7.03013) | extracellular space | diagnosis, progression, prognosis | other |
CD274 | 0 | 0.399799 | (0.178413)/(0.132517) | 1.91475 | 2.59352 | (0.876092)/(0.132517) | plasma membrane | Â | enzyme |
ABCB1 | 0 | −0.82259 | (0.0369124)/(0.0675486) | −1.16348 | −3.15243 | (0.00427968)/(0.0675486) | plasma membrane | prognosis | transporter |
INHBA | 0 | 0.144985 | (0.0889291)/(0.0781141) | 1.8329 | 3.13707 | (0.807319)/(0.0781141) | extracellular space | diagnosis | growth factor |
