Table 1 Baseline demographic characteristics and cardiovascular risk factors between groups with/without asymptomatic carotid stenosis.

From: Homocysteine and Its Relationship to Asymptomatic Carotid Stenosis in a Chinese Community Population

 

Without Asymptomatic CAS (n = 5032)

With Asymptomatic CAS (n = 361)

p

Age, y, Median(Q1-Q3)(n)

52.32(45.64–60.90)

57.02(46.20–74.05)

<0.0001

Ethnic group (Han) n(%)

4962 (98.6%)

354(98.1%)

0.3575

Gender n(%)

  

<0.0001

 Male

2924(58.1%)

302(83.7%)

 

 Female

2108(41.9%)

59(16.3%)

 

Current smoking n(%)

1548(30.76%)

169(47.0%)

<0.001

Hypertension n(%)

2395(47.6%)

196(54.3%)

0.0142

Diabetes mellitus n(%)

589 (11.7%)

58(16.1%)

0.0185

Hyperlipidemia n(%)

2330(46.3%)

156(43.2%)

0.2744

Antihypertensive drugs n(%)

957(19.0%)

90(24.9%)

0.0061

Lipid-lowering drugs n(%)

69(1.4%)

6(1.7%)

0.6485

Antidiabetic drugs n(%)

293(5.8%)

32(8.9%)

0.0190

Atrial fibrillation n(%)

69(1.4%)

9/361 (2.5%)

0.1038

BMI level(kg/m 2 ) Median(Q1-Q3)(n)

24.77(22.76–27.05)

24.09(21.97–26.57)

<0.0001

 <25 n(%)

2656 (52.8%)

228 (63.2%)

0.0003

 25–30 n(%)

2041 (40.6%)

120 (33.2%)

 

 >30 n(%)

335 (6.7%)

13 (3.6%)

 

hs-CRP,mg/dL Median(Q1-Q3)(n)

1.0(0.5–2.14)

1.1(0.6–2.95)

0.0054

Hcy (μmol/L) Median(Q1-Q3)(n)

13.4(9.5–19.0)

16.3(11.9–22.8)

<0.0001

 1st tile(<9.6) n(%)

1316 (26.2%)

50 (12.9%)

<0.0001

 2st tile(9.6~13.6) n(%)

1257 (25.0%)

76 (21.1%)

 

 3st tile(13.6~19.3) n(%)

1256 (25.0%)

92 (25.6%)

 

 4st tile(>19.3) n(%)

1203 (23.9%)

143 (39.6%)

 
  1. Values are median (interquartile range) or number (percent).CAS: carotid stenosis; BMI: body mass index; hs-CRP: high-sensitivity C reactive protein; Hcy: homocysteine.