Table 3 Multivariate-adjusted OR and 95%CI for asymptomatic carotid stenosis according to quartile of homocysteine, stratified by age, gender and selected risk factors.

From: Homocysteine and Its Relationship to Asymptomatic Carotid Stenosis in a Chinese Community Population

 

Quartile of homocysteine (μmol/L)

Continuous Scale

P interaction

1st tile(<9.6)

2st tile(9.6 ~ 13.6)

3st tile(13.6 ~ 19.3)

4st tile(>19.3)

Age

     

0.76

 <60y

1

1.33(0.85–2.10)

1.56(0.99–2.46)

1.60(1.01–2.53)*

1.01(0.99–1.02)

 

 ≥60y

1

0.98(0.46–2.06)

0.85(0.41–1.76)

1.03(0.51–2.10)

0.99(0.97–1.01)

 

gender

     

0.44

 Female

1

1.27(0.68–2.39)

0.72(0.30–1.70)

1.71(0.76–3.87)

1.02(0.98–1.06)

 

 Male

1

1.26(0.77–2.04)

1.39(0.88–2.22)

1.60(1.02–2.52)*

1.00(0.99–1.01)

 

Hypertension

     

0.74

 No

1

1.53(0.91–2.57)

1.36(0.79–2.33)

2.05(1.22–3.44)*

1.01(0.99–1.03)

 

 Yes

1

0.97(0.55–1.70)

1.08(0.63–1.85)

1.11(0.65–1.91)

1.00(0.98–1.01)

 

Diabetes

     

0.04

 No

1

1.13(0.74–1.71)

1.30(0.87–1.95)

1.42(0.95–2.12)

1.00(0.99–1.01)

 

 Yes

1

2.19(0.77–6.27)

0.90(0.28–2.86)

2.89(1.02–8.22)*

1.02(0.99–1.05)

 

Hyperlipidemia

     

0.59

 No

1

1.63(0.97–2.76)

1.59(0.94–2.68)

2.16(1.29–3.64)*

1.01(0.99–1.02)

 

 Yes

1

0.88(0.50–1.53)

0.90(0.52–1.56)

1.01(0.59–1.74)

1.00(0.98–1.02)

 
  1. *P < 0.05.
  2. OR: odd ratio; CI: confidence interval.
  3. Adjusted for age, gender, BMI, hypertension, diabetes, hyperlipidemia, antihypertensive drugs, lipid-lowering drugs, antidiabetic drugs, current smoking and hs-CRP.