Figure 4
Contact hypersensitivity (CHS) was performed to compare the levels of immunosuppression after indicated UVB treatment.
(A) The representative presentation of ear swelling response after indicated treatment. The increase in ear thickness was defined as the amount of swelling of the 2,4,-dinitrofluorobenzene (DNFB)-challenged ear as compared to the thickness of vehicle treated ear. Upper Left: control mouse with no prior sensitization; Lower Left: Positive control mouse with prior sensitization; Upper Right: high irradiance (HI) UVB treated mouse before sensitization; Lower Right: low irradiance (LI) UVB treated mouse before sensitization. (B) The quantitative analyses of increase in ear thickness after indicated treatment. Sham: control mice with no prior sensitization; Control: mice with prior sensitization; HI UVB: mice treated with HI UVB prior to sensitization; LI UVB: mice treated with LI UVB treated mice prior to sensitization. *Indicates p < 0.05 as compared to sham treated group; **Indicates p < 0.05.
