Table 3 Type I error rates of four tests based on simulation set 1 for quantitative traits.
Number of Subpopulations | Test | Alpha | Un-corrected | GC | PC-linear | PC-nonp |
---|---|---|---|---|---|---|
2 | Single Variant | 0.01 | 0.1516 | 0.00414 | 0.01026 | 0.01038 |
0.001 | 0.05998 | 0.00032 | 0.00108 | 0.001 | ||
Regional | 0.01 | 0.258 | 0.0081 | 0.00995 | 0.00925 | |
0.001 | 0.1489 | 0.0004 | 0.00115 | 0.00095 | ||
10 | Single Variant | 0.01 | 0.0503 | 0.01498 | 0.01096 | 0.01068 |
0.001 | 0.01606 | 0.0026 | 0.0012 | 0.00108 | ||
Regional | 0.01 | 0.0549 | 0.0101 | 0.0107 | 0.0102 | |
0.001 | 0.0139 | 0.00085 | 0.0008 | 0.001 | ||
20 | Single Variant | 0.01 | 0.04896 | 0.02602 | 0.04234 | 0.01004 |
0.001 | 0.0214 | 0.0102 | 0.01632 | 0.00082 | ||
Regional | 0.01 | 0.0488 | 0.01285 | 0.0391 | 0.011 | |
0.001 | 0.0137 | 0.00255 | 0.0096 | 0.00075 |