Table 4 Type I error rates of five tests based on simulation set 1 for qualitative traits.
Number of Subpopulations | Test | Alpha | Un-corrected | GC | PC-linear | Biased Perm | PC-nonp |
---|---|---|---|---|---|---|---|
2 | Single Variant | 0.01 | 0.02914 | 0.00648 | 0.01124 | 0.0065 | 0.0107 |
0.001 | 0.00592 | 0.00034 | 0.00094 | 0.00056 | 0.00094 | ||
Regional | 0.01 | 0.04066 | 0.00924 | 0.01168 | 0.0103 | 0.01192 | |
0.001 | 0.0093 | 0.0009 | 0.00144 | 0.001 | 0.00146 | ||
10 | Single Variant | 0.01 | 0.0428 | 0.01106 | 0.0106 | 0.00672 | 0.0103 |
0.001 | 0.01172 | 0.00124 | 0.00162 | 0.00078 | 0.00138 | ||
Regional | 0.01 | 0.04862 | 0.00984 | 0.0105 | 0.01034 | 0.01062 | |
0.001 | 0.01174 | 0.00134 | 0.00128 | 0.0008 | 0.0012 | ||
20 | Single Variant | 0.01 | 0.02022 | 0.01244 | 0.01734 | 0.02296 | 0.01072 |
0.001 | 0.00414 | 0.00138 | 0.00354 | 0.00458 | 0.00132 | ||
Regional | 0.01 | 0.04014 | 0.01068 | 0.03468 | 0.02694 | 0.01034 | |
0.001 | 0.00952 | 0.00172 | 0.00746 | 0.0051 | 0.00152 |