Table 5 Type I error rates of four tests based on simulation set 2 for quantitative traits.

From: A Nonparametric Regression Approach to Control for Population Stratification in Rare Variant Association Studies

Model

Test

Alpha

Un-corrected

GC

PC-linear

PC-nonp

1

Single Variant

0.01

0.0207

0.0135

0.0228

0.0132

0.001

0.0042

0.0021

0.0048

0.0014

Regional

0.01

0.1256

0.0121

0.1171

0.0106

0.001

0.052

0.0024

0.0463

0.0008

2

Single Variant

0.01

0.019

0.0139

0.011

0.0115

0.001

0.0048

0.0026

0.0011

0.0011

Regional

0.01

0.0374

0.0128

0.0112

0.0082

0.001

0.0102

0.0009

0.0008

0.0006

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