Figure 3 | Scientific Reports

Figure 3

From: Continuous single cell imaging reveals sequential steps of plasmacytoid dendritic cell development from common dendritic cell progenitors

Figure 3

Time-dependent occurrence of cell types in CDP genealogies.

CDPs were cultured on EL08 feeder cells with Flt3L for 5 days and their progeny were observed continuously by single cell imaging and tracking. (A) The time until first occurrence of fluorescent markers in the pedigrees was determined. (B) The time until first occurrence of each cell type in the pedigrees was calculated as weighted mean. Data are shown as box plots with whiskers and outliers, median values indicated by horizontal lines. Significant differences are indicated by an asterisk (p < 0.05, Kruskall-Wallis-test with Dunn’s post test).

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