Table 1 Characteristics of the registered CHB patients.

From: Female gender lost protective effect against disease progression in elderly patients with chronic hepatitis B

 

Non-cirrhotic CHB

Cirrhotic CHB

Total n = 14,508

Male n = 10,290

Female n = 4218

Total n = 3301

Male n = 2414

Female n = 887

Age, year

40 (32, 50)

40 (32, 48)

40 (31, 52)

51 (43, 59)

50 (42, 58)

56 (48, 62)

HBeAg positive rate, %

3761 (56.8%)

2684 (55.9%)

1077 (59.2%)

494 (44.4%)

363 (41.8%)

131 (53.5%)

HBV DNA, log IU/ml

3.64 (2.30, 6.05)

3.66 (2.30, 5.94)

3.60 (2.30, 6.24)

2.58 (0, 4.79)

2.63 (0, 4.84)

2.56 (0, 4.49)

PLT count, ×109/L

172.0 (133.0, 210.0)

169.0 (131.0, 208.0)

179.0 (136.0, 220.0)

94.0 (59.0, 139.0)

97.0 (63.0, 143.0)

84.0 (52.1, 133.0)

ALT, IU/mL

35.0 (22.0, 66.1)

38.0 (24.0, 70.0)

27.0 (17.0, 55.4)

32.1 (23.0, 49.0)

34.0 (24.0, 49.8)

28.9 (19.9, 45.0)

AST, IU/mL

30.0 (22.5, 48.7)

30.3 (23.0, 49.0)

28.0 (20.7, 47.0)

32.6 (22.0, 51.0)

33.0 (23.0, 50.0)

32.0 (20.0, 52.0)

Albumin, g/L

45.1 (42.0, 47.4)

45.6 (42.4, 47.8)

44.0 (41.2, 46.3)

40.7 (34.0, 45.6)

41.4 (34.5, 46.0)

38.6 (32.9, 44.0)

Bilirubin, mol/L

13.8 (10.5, 18.5)

14.6 (11.2, 19.5)

12.1 (9.2, 15.4)

19.0 (13.2, 28.7)

19.2 (13.5, 29.2)

17.8 (12.6, 26.5)

CHE, IU/L

8058.0 (6633.5, 9590.5)

8426.5 (6788.0, 9891.0)

7595.0 (6222.0, 8692.0)

4868.5 (3039.5, 7108.0)

4803.0 (3043.0, 7277.0)

4877.0 (2973.0, 6615.5)

ALP, U/L

72.0 (59.0, 91.0)

75.0 (61.0, 92.0)

66.0 (54.0, 86.0)

86.0 (67.0, 117.0)

86.0 (68.0, 117.0)

87.0 (64.1, 117.0)

GGT, U/L

26.0 (17.0, 47.3)

30.0 (20.0, 55.1)

18.0 (13.0, 31.2)

45.0 (25.3, 80.0)

49.0 (28.0, 87.0)

36.0 (22.0, 63.0)

Cr, mol/L

71.6 (61.0, 81.5)

75.0 (67.0, 84.0)

55.0 (49.0, 63.7)

69.0 (58.0, 80.0)

72.3 (64.0, 83.0)

55.3 (48.0, 67.0)

Cholesterol, mmol/L

4.3 (3.8, 5.1)

4.3 (3.7, 5.1)

4.5 (3.9, 5.1)

3.6 (2.9, 4.4)

3.7 (3.0, 4.5)

3.6 (2.9, 4.3)

Triglyceride, mmol/L

1.1 (0.8, 1.7)

1.2 (0.8, 1.8)

1.0 (0.7, 1.4)

0.9 (0.6, 1.3)

0.9 (0.7, 1.3)

0.8 (0.6, 1.1)

PTA, %

102.0 (88.0, 118.0)

101.0 (87.0, 117.0)

103.0 (90.0, 120.0)

74.0 (59.0, 90.0)

72.0 (58.0, 89.0)

76.0 (63.3, 92.0)

INR, ratio

1.0 (0.9, 1.1)

1.0 (0.9, 1.1)

1.0 (0.9, 1.0)

1.1 (1.0, 1.3)

1.2 (1.0, 1.3)

1.1 (1.0, 1.3)

  1. Data were presented by median (lower quartile, upper quartile).
  2. CHB, chronic hepatitis B; PLT, platelet; ALT, alanine aminotransferase; AST, aspartate aminotransferase; CHE, cholinesterase; ALP, alkaline phosphatase; GGT, gamma glutamyltransferase; Cr, creatinine; PTA, prothrombin activity; INR, international normalized ratio of prothrombin time.
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