Figure 1

Expressions of BMP-2 mRNA and protein in HepG2 cells.
(A) BMP-2 mRNA expression level is significantly lower in LV-SH-BMP2-C group than in LV-SH-BMP2-A and in LV-SH-BMP2-B groups. BMP-2 mRNA expression level is significantly higher in overexpression-LV-BMP2 group than in overexpression-LV-CON group. (B) Results of BMP-2 protein expression detected by western blot analysis in different groups (C) BMP-2 protein expression level is significantly lower in LV-SH-BMP2-C group than in LV-SH-BMP2-A and in LV-SH-BMP2-B groups. BMP-2 protein expression level is significantly higher in overexpression-LV-BMP2 group than in overexpression-LV-CON group. Notes: BMP-2: Bone morphogenetic protein 2; LV-SH-BMP2: lentivirus vectors expressing small hairpin RNA against BMP-2 gene. *Indicates P < 0.05 as compared with other groups.