Figure 2

HUVEC proliferation.
(A) HUVEC proliferation is significantly inhibited in LV-SH-BMP2 group as compared with those in LV-SH-CON and CON groups (all P < 0.05). But no significant difference is found between LV-SH-CON and CON groups in HUVEC proliferation (P > 0.05). HUVEC proliferation is significantly inhibited in LV-SH-BMP2 group as compared with those in LV-SH-CON and CON groups (all P < 0.05). (B) HUVEC proliferation is significantly higher in overexpression–LV-BMP2 group than in overexpression–LV-BMP2 and CON groups (all P < 0.05). Notes: BMP-2: Bone morphogenetic protein 2; HUVEC: human umbilical vein endothelial cell; LV-SH-BMP2: lentivirus vectors expressing small hairpin RNA against BMP-2 gene.