Table 3 Correlation between functional/structural connectivity and cognition measurements.

From: Structural and Functional Connectivity of Default Mode Network underlying the Cognitive Impairment in Late-onset Depression

Items

Statistics

MMSE

AVLT

VFT

DST

TMT-A

TMT-B

SDMT

PCC/Pcu to dACC

 FC

r

0.318

0.345*

0.362*

0.448*

−0.372*

−0.205

0.428*

 (N = 62)

P

0.012

0.006

0.004

0.000

0.003

0.110

0.001

 FA

r

0.256

0.065

0.258

0.345*

−0.027

−0.155

0.311*

 (N = 55)

P

0.062

0.638

0.059

0.011

0.847

0.263

0.022

 MD

r

−0.265

−0.174

−0.266

−0.208

0.038

0.056

−.277*

 (N = 55)

P

0.053

0.209

0.051

0.131

0.784

0.687

0.042

 AD

r

−0.092

−0.159

−0.156

−0.002

0.079

−0.008

−0.149

 (N = 55)

P

0.508

0.251

0.261

0.990

0.572

0.955

0.282

 RD

r

−0.304*

−0.157

−0.279*

−0.270*

0.015

0.076

−.296*

 (N = 55)

P

0.025

0.258

0.041

0.048

0.913

0.583

0.030

 FN

r

0.045

0.031

0.145

0.038

−0.120

0.049

−0.034

 (N = 55)

P

0.749

0.822

0.297

0.787

0.386

0.728

0.809

PCC/Pcu to thalamus

 FC

r

0.200

0.249

0.306*

0.186

−0.235

−0.050

0.306*

 (N = 62)

P

0.120

0.051

0.015

0.148

0.066

0.697

0.016

 FA

r

0.238

0.163

0.425

0.489

−0.366

−0.333

0.544*

 (N = 14)

P

0.413

0.577

0.130

0.076

0.198

0.244

0.044

 MD

r

−0.175

−0.002

−0.285

−0.311

0.397

0.381

−0.457

 (N = 14)

P

0.550

0.995

0.322

0.280

0.159

0.179

0.100

 AD

r

−0.228

0.037

−0.075

0.031

0.347

0.271

−0.358

 (N = 14)

P

0.434

0.899

0.799

0.916

0.224

0.349

0.209

 RD

r

−0.140

−0.015

−0.333

−0.401

0.378

0.384

−0.449

 (N = 14)

P

0.633

0.958

0.245

0.155

0.183

0.176

0.107

 FN

r

−0.507

−0.169

−0.369

−0.154

0.265

0.112

−0.177

 (N = 14)

P

0.064

0.565

0.194

0.600

0.360

0.703

0.544

  1. Notes: P value was calculated by partial correlation analysis, taking age and education as the covariate; *P < 0.05.
  2. Abbreviation: MMSE, Mini mental state exam; AVLT, Auditory Verbal Learning Test; DST, Digit span test-forward and backward; VFT, Verbal fluency test-animal and verb; TMT, Trail making test; SDMT, Symbol digit modalities test;. PCC/Pcu, posterior cingulate cortex/precuneus; dACC, dorsal anterior cingulate; FC, functional connectivity; FA, Fractional anisotropy; RD, radial diffusivity; MD, mean diffusivity; AD, axial diffusivity; FN, fiber number.