Figure 4
From: Oligofructose as an adjunct in treatment of diabetes in NOD mice
(A) Insulitis score, (B) percentage of insulitis-free islets, and (C) total insulitis score were compared between the aCD3 and the aCD3 + OFS group at the end of the 8-week treatment. (n = 4–6 mice/treatment group, at least 20 islets were counted from each mouse). (D) Percentage of Foxp3-positive cells in the pancreatic islets and pancreatic lymph nodes. Representative images of pancreatic lymph nodes, immunostained for Foxp3 (red) are shown. (n = 2–3 mice/treatment group, at least 3500 cells were counted for each group).
