Figure 2 | Scientific Reports

Figure 2

From: Preparation of 6/8/11-Amino/Chloro-Oxoisoaporphine and Group-10 Metal Complexes and Evaluation of Their in Vitro and in Vivo Antitumor Activity

Figure 2

Synthetic routes for group-10 metal(II) complexes 7–11 of 8-chloro-oxoisoaporphine (Lc).

Reagents and solvents are the following: (a) cis-Pt(DMSO)2Cl2, ethanol/water (v/v = 20:1) (80 °C); (b) 1,2-ethylenediamine or 1,3-propanediamine, anhydrous ethanol (reflux); (c) cis-Pt(DMSO)2Cl2, methanol/CH3CN (v/v = 20:1) (80 °C); (d) 1,2-ethylenediamine, anhydrous ethanol (reflux).

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