Table 2 FID assay for 1–6 interactions with DNA.

From: Preparation of 6/8/11-Amino/Chloro-Oxoisoaporphine and Group-10 Metal Complexes and Evaluation of Their in Vitro and in Vivo Antitumor Activity

 

1

2

3

4

5

6

7

10

Pu27DC50 (ctDNADC50/Pu27DC50)

1.31 (45.90)

3.88 (4.80)

0.75 (130.49)

14.22 (6.21)

42.51 (1.82)

12.35 (7.45)

60.02 (1.67)

33.15 (2.98)

HTG21DC50 (ctDNADC50/HTG21DC50)

3.35 (17.95)

3.91 (4.76)

1.52 (64.81)

26.45 (3.34)

49.08 (1.58)

19.87 (4.63)

70.83 (1.41)

55.16 (1.79)

c-kit-2DC50 (ctDNADC50/c-kit-2DC50)

3.61 (16.66)

5.01 (3.71)

2.25 (43.50)

45.30 (1.95)

>100 (<0.77)

55.28 (1.66)

87.29 (1.15)

79.69 (1.24)

c-kit-1DC50 (ctDNADC50/c-kit-1DC50)

9.11 (6.60)

18.75 (0.99)

2.33 (42.00)

73.65 (1.20)

78.46 (0.98)

71.64 (1.28)

90.02 (1.11)

79.95 (1.23)

Pu22DC50 (ctDNADC50/Pu22DC50)

7.63 (7.88)

9.09 (2.05)

4.78 (20.47)

90.18 (0.98)

89.64 (0.86)

42.61 (2.16)

99.81 (1.01)

74.91 (1.32)

ds26DC50 (ctDNADC50/ds26DC50)

37.01 (1.62)

21.76 (0.86)

23.03 (4.25)

70.46 (1.25)

90.63 (0.85)

57.71 (1.59)

96.11 (1.04)

91.48 (1.07)

ctDNADC50 (ctDNADC50/ctDNADC50)

60.13 (1.00)

18.61 (1.00)

97.87 (1.00)

88.29 (1.00)

77.37 (1.00)

91.97 (1.00)

99.99 (1.00)

98.64 (1.00)

Back to article page