Figure 6 | Scientific Reports

Figure 6

From: Functional Improvement and Regression of Medial Hypertrophy in the Remodeled Pulmonary Artery after Correction of Systemic Left-to-Right Shunt

Figure 6

Representative blots of protein expressions of smooth muscle myosin heavy chain (SM-MHC)-II, α-smooth muscle actin (SMA), desmin and matrix metalloproteases (MMP)-2 in the isolated pulmonary artery of experimental rats.

Ligation of aortocaval fistula restored the synthetic to contractile phenotyping of vascular smooth muscle cells by enhanced expressions of SM-MHC-II and α-SMA, and suppressed expression of desmin. *P < 0.05 compared with non-ligation group. n = 6 different animals in each group. Each band represents an independent tissue sample obtained from a different animal and the bands were visualized using an automated imaging system (UPV BioSpectrum) under the same experimental conditions. Data were analyzed by one-way ANOVA and are shown as mean ± SD.

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